J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal

Johnson & Johnson said on Monday it would buy neurological drugmaker Intra-Cellular Therapies for $14.6 billion, its biggest deal in more than two years, boosting its presence in the market for brain disease treatments. The deal would help accelerate growth in J&J’s drugs business after the company spun off its consumer health unit in 2023. It has made several transactions in the past few years to boost its pharmaceuticals and medical devices units, including a $13.1 billion deal for Shockwave Medical in 2024.

J&J has offered to buy each share of Intra-Cellular for $132, representing a 39% premium to the stock’s closing price on Friday. Shares of Intra-Cellular rose 35% to $128 in early trading, while J&J was up marginally. The deal would allow J&J gain access to Intra-Cellular’s oral therapy, Caplyta, which is approved in the U.S. to treat schizophrenia and depressive episodes associated with bipolar disorder, and other experimental drugs under development.

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Caplyta brought in $481.3 million in sales in the first nine months of 2024 and does not face generic competition until 2040. Analysts expect the treatment to bring in more than $1 billion in sales next year, according to data compiled by LSEG.The transaction comes on the heels of a major industry conference starting on Monday in San Francisco. Ahead of the deal’s announcement, healthcare dealmakers had said they expect a resurgence of deals exceeding $10 billion due to the potential for less antitrust scrutiny under President-elect Donald Trump.

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RBC Capital analyst Shagun Singh said the deal fit strategically into J&J’s neurological drugs division, an important area for the company. But at least one investor raised concerns that it could potentially face a tougher antitrust review.”I do have a lot of antitrust concerns about this deal,” said Jeff Jonas, portfolio manager at Gabelli Funds, which owns about 193,035 shares of J&J.

Jonas said there was an overlap in the products of the two companies, given J&J has a late-stage depression drug and a schizophrenia treatment already on the market. J&J’s expectation that it would close the deal “later this year” seems to incorporate a tough review even under the new administration, he said.

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